CYP1A2 Raw DNA Analysis & Clinical Evidence
Discover whether you are a fast or slow caffeine metabolizer via CYP1A2*1F. Evidence Grade B with PubMed citations.
Analyze your CYP1A2 variants locally in your browser
Drop your raw 23andMe or AncestryDNA file into Verinome. It is parsed locally in your browser, so your raw file never uploads. To build the full report, only about 200 marker readouts (a few kilobytes, never your file and never your name) are checked. Educational and evidence-graded, not a diagnosis, bring anything clinical to your own clinician.
Published Evidence & Guideline Context for CYP1A2
You likely clear caffeine relatively quickly. Fast metabolizers tend to feel caffeine's effects wear off sooner. Clinical/health relevance of this SNP is debated.
Source: Cornelis MC et al., JAMA 2006;295:1135-41, PMID 16522832
One faster and one slower copy. Often grouped with slower caffeine metabolizers. Effect is modest and context-dependent.
Source: Cornelis MC et al., JAMA 2006;295:1135-41, PMID 16522832
You may clear caffeine more slowly, so effects can linger. Some studies link slow metabolizers + heavy coffee to higher blood-pressure/heart risk, but findings are inconsistent.
Source: Cornelis MC et al., JAMA 2006;295:1135-41, PMID 16522832