Activates the blood-thinner clopidogrel (Plavix) faster than average.
Backed by CPIC Level 1A guidance and replicated clinical outcomes. Informational, bring any medication question to your prescriber.
Most DNA sites present a single-SNP hunch with the same confidence as replicated clinical science. We put a grade on every finding, how strong the research behind it actually is, and we don’t hide the D’s.
How you activate the blood-thinner clopidogrel is backed by CPIC Level 1A guidelines and replicated clinical outcomes. Worth bringing to a physician.
Early studies linked one OXTR variant to higher empathy and it travelled a long way in popular science. Later, larger work did not reproduce it. Fun to know, not something to build decisions on, so we label it exactly that.
Large, replicated studies or a clinical guideline (e.g. CPIC). Confident science.
Several consistent studies, but not yet guideline-grade. Reasonable to consider.
A few studies, mixed or small. Interesting, not decisive.
Single small studies or popular myths. Shown for curiosity, clearly labeled.
How it’s curated: pharmacogenomics follows peer-reviewed CPIC clinical guidelines, carrier findings cite ClinVar, and traits cite the primary studies behind them. Every finding in your report carries its source, and weak evidence is graded D and labeled, never dressed up.
Read the full methodology, compatibility matrix and array limits →
Pharmacogenomics lead with your metabolizer status; traits show where you sit against the population. Both carry a grade and a plain line, no jargon walls, no odds ratios.
Table 2, interactive sample · illustrative data
Activates the blood-thinner clopidogrel (Plavix) faster than average.
Backed by CPIC Level 1A guidance and replicated clinical outcomes. Informational, bring any medication question to your prescriber.
CPIC associates this variant with increased warfarin sensitivity, context for your prescriber.
CPIC Level 1A. Consumer-array result, not a clinical test, confirm with a clinician before any dosing decision.
Codeine may give you less pain relief than average, your body converts it to its active form more slowly.
CPIC Level 1A. For codeine this is a less-effect story, not a buildup, reduced CYP2D6 activity means less conversion to the active form. A detail for your prescriber, not a change to make yourself.
Some statins may be more likely to cause muscle side effects for you.
Several consistent studies; not yet a formal high-level guideline for every statin. A useful conversation to have, not a directive.
Caffeine clears more slowly for you than for most people.
Consistent across several studies. Explains why an afternoon coffee might hit you harder, genuinely useful, low-stakes.
A genetic predisposition toward lower levels, not a measurement.
GWAS across 8 studies. Your actual level depends on sun, diet, and more. Ancestry affects accuracy.
Your variant is associated with lactase persistence into adulthood.
Well studied in some ancestries, less so in others, so we grade it Limited for a general audience. Interesting, not decisive.
A commonly-hyped variant with a modest, often-overstated effect.
Heavily marketed online, but the evidence for most claims is limited. We show it and tell you plainly not to over-read it.
An early, widely repeated claim that larger studies did not reproduce.
Fun to read, not science to act on, so it’s Grade D. We keep it in precisely so you can see where the weak evidence is.
No results at this grade in the sample.
Your 23andMe or Ancestry file comes from a genotyping chip that measures specific positions, roughly 600,000 to 700,000 of your ~3.2 billion base pairs. That is about 0.02%. Verinome reads those exact positions honestly and flags when a result may be uncertain. It is not whole-genome sequencing and cannot detect most rare disease variants, which is exactly why every finding carries an evidence grade and points you to a clinician for anything clinical.
Your file, parsed on your device, every result carrying the grade it earned.
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