CYP2C19 · clopidogrel
Rapid metabolizer
Activates the blood-thinner clopidogrel (Plavix) faster than average.
Backed by CPIC Level 1A guidance and replicated clinical outcomes. Informational, bring any medication question to your prescriber.
1.0 · The honest difference
Every result carries its evidence grade. We show you the weak ones too.
Most DNA sites present a single-SNP hunch with the same confidence as replicated clinical science. We put a grade on every finding, how strong the research behind it actually is, and we don’t hide the D’s.
A versus D: the same report, honestly labeled
A
CYP2C19 & clopidogrel
How you activate the blood-thinner clopidogrel is backed by CPIC Level 1A guidelines and replicated clinical outcomes. Worth bringing to a physician.
CPIC 1A, Replicated
Grade A, large studies, replicated, clinical guideline
D
COMT “warrior / worrier”
The popular idea that one COMT variant makes you a “warrior” or “worrier” rests on small, inconsistent studies. Fun, but not something to build decisions on, so we label it exactly that.
Not replicated
Grade D, small samples, conflicting, not replicated
A
Strong
Large, replicated studies or a clinical guideline (e.g. CPIC). Confident science.
B
Moderate
Several consistent studies, but not yet guideline-grade. Reasonable to consider.
C
Limited
A few studies, mixed or small. Interesting, not decisive.
D
Weak
Single small studies or popular myths. Shown for curiosity, clearly labeled.
2.0 · Sample report
What a Verinome result actually looks like.
Pharmacogenomics lead with your metabolizer status; traits show where you sit against the population. Both carry a grade and a plain line, no jargon walls, no odds ratios.
Table 2, interactive sample · illustrative data
click a grade to filter · click a card to expand
A
VKORC1 · warfarin
Increased sensitivity
CPIC associates this variant with increased warfarin sensitivity, context for your prescriber.
CPIC Level 1A. Consumer-array result, not a clinical test, confirm with a clinician before any dosing decision.
CYP2D6 · codeine
Intermediate metabolizer
Codeine may give you less pain relief than average, your body converts it to its active form more slowly.
CPIC Level 1A. For codeine this is a less-effect story, not a buildup, reduced CYP2D6 activity means less conversion to the active form. A detail for your prescriber, not a change to make yourself.
SLCO1B1 · statins
Higher myopathy association
Some statins may be more likely to cause muscle side effects for you.
Several consistent studies; not yet a formal high-level guideline for every statin. A useful conversation to have, not a directive.
CYP1A2 · caffeine
Slow metabolizer 78th pct
Caffeine clears more slowly for you than for most people.
Consistent across several studies. Explains why an afternoon coffee might hit you harder, genuinely useful, low-stakes.
Vitamin D level
Tends lower 62nd pct
A genetic predisposition toward lower levels, not a measurement.
HigherAverageLower
GWAS across 8 studies. Your actual level depends on sun, diet, and more. Ancestry affects accuracy.
MCM6 · lactose
Likely tolerant
Your variant is associated with lactase persistence into adulthood.
Well studied in some ancestries, less so in others, so we grade it Limited for a general audience. Interesting, not decisive.
MTHFR · C677T
One copy
A commonly-hyped variant with a modest, often-overstated effect.
Heavily marketed online, but the evidence for most claims is limited. We show it and tell you plainly not to over-read it.
COMT · rs4680
“Warrior / worrier”, inconclusive
The popular personality claim rests on small, inconsistent studies.
Fun to read, not science to act on, so it’s Grade D. We keep it in precisely so you can see where the weak evidence is.
No results at this grade in the sample.
3.0 · Begin analysis
Ready to see yours, graded?
Your file, parsed on your device, every result carrying the grade it earned.
30-day, no-questions refund, your reports stay yours even if you refund.